Demi Moore gives a career-best performance as Elisabeth Sparkle, a former A-lister past her prime and suddenly fired from her fitness TV show by repellent studio head Harvey (Dennis Quaid). She is then drawn to the opportunity presented by a mysterious new drug: The Substance. All it takes is one injection and she is reborn – temporarily – as the gorgeous, twentysomething Sue (Margaret Qualley).
The only rule? Time needs to be split: exactly one week in one body, then one week in the other. No exceptions. A perfect balance. What could go wrong?
Deliriously entertaining and ruthlessly satirical, Coralie Fargeat’s The Substance won Best Screenplay at Cannes 2024, the Golden Globe for Best Performance by a Female Actor and is a strong contender at the BAFTA and Academy Awards this year.
Followed by a Q&A with actor Demi Moore and director Coralie Fargeat